Cardio-Metabolic

NEUGAPIN

  • In Neuropathic Pain Management
  • Pregabalin 75mg with
    Methylcobalamin 1500mcg
  • Tablets

Pregabalin

  • Reduces neurotransmitter release Reduces neuropathic pain

Methylcobalamin

  • Promotes Myelination Augment Sensory & Motor function

Key Benefits -

  • 72.30/o reduction in Pain score in 2 weeks
  • Effect starts within weeks time
  • Efficacy and tolerability rated as good to excellent by > 95%
    patients

Remyelination
ensures long
term relief

Prevents the
progression of
Neuropathy

Relives painful
Neuropathy
symptoms

  • Rebuild
    Nerves,
    Rejuvenate
    GRIT

HEFGINA

  • Trimetazidine 35 mg Modified
    Release Tablets

Improve L V Function in DM

  • In DM, the myocardial glucose utilization is impaired. Leads to
    decreased myocyte glucose uptake & high FFA
  • TMZ Improve L V in diabetics & Improve left ventricular
    ejection fraction (L VEF)

Reduce Myocardial Demand

  • Switches mitochondrial ATP formation from FFA to Glucose.
    (Inhibits 3-ketoacyl coenzyme A thiolase in FFA oxidation)
  • Glycolysis requires 10%-15% less 02 than FF A oxidation to
    yield same ATP

Improve
endothelial
function

Controls ischemia
through intracellular
metabolic changes

Reduces
reperfusion
injury

  • Empower
    cardiomyocytes
    in Angina & MI
    patients

Enhances the
duration of
coronary flow.

Reduces MVO & thus O consumption

Reduces Heart
Rate, Prolongs
Diastole

Benziva

  • The Primary Adjuvant
  • Ivabradine 5mg Tablets

Similar to Beta Blocker

  • Reduction in heart rate is similar to that with beta-blockers

Develop Collaterals

Promote development of coronary collaterals

  • Minimal effect on myocardial contractility, BP and intracardiac conduction

Powerful Therapy

  • In patients who are intolerant or Contraindicated to Beta blockers
  • In patients with higher HR & uncontrolled with BB optimum dose
  • In Stable
    angina &
    ACS
  • 2
  • 2
  • Gliclazide 30mg 60mg

Mechanism of Action

  • Gliclazide stimulates insulin secretion thought the beta cell
    sulphonylurea receptor

Benefits

  • Shows gradual improvement in glycemic condition
  • Lower the risk of Hypoglycemia
  • Reduces risk of cardiovascular disease
  • Reduces Oxidative stress, inflammation & bone loss

Reduces
Insulin
Resistance

Decrease expression of
inflammatory markers &
endothelium Dysfunction

Gives
Cardiovascular
Protection

  • Revolutionize
    diabetes
    management
    with Gliclazide

SECGLY

  • Tablets
  • Rosuvastatin 10mg, Ezetimibe 10mg

Benefits

  • Ezetimibe inhibits cholesterol absorption
    from the small intestine
  • Improves Vascular Endothelial Dysfunction
    in ACS

Reduction in LDL-C
Levels

  • Rosuvastatin 10mg / 20mg

Benefits

  • Provides LDL-C reduction even in
    patients shifted from Atorvastatin
  • Provides greatest reduction in LDL-C in
    women with Hypercholesterolemia
  • Superior to atorvastatin in the reversion
    of coronary Atherosclerotic Plaques

Highest increase in HDL-C
compared to all other
statins at recommended
doses (
STELLAR study)

Provides LDL-C reduction
even
in patients shifted
from Atorvastatin

Stateze RZ

  • Tablets

Stateze R 10 20

  • Tablets